Isla Fisher looks set to be the leading lady in a new romantic comedy about a woman able to tell how a relationship will pan out by the quality of the first kiss.

The actress, who grew up in Perth and will soon marry Sacha Baron Cohen, shone as a crazy bridesmaid in Wedding Crashers with Vince Vaughn and Owen Wilson and is known for her comedic ability.

Up in the Air Oscar nominee Sheldon Turner will co-produce the flick, to be called Kiss and Tell, according to Variety.

Fisher has carved a career by choosing quirky characters in humorous flicks.

She starred in Defninitely Maybe opposite Ryan Reynolds, Confessions of a Shopaholic, Scooby-Doo and Wedding Daze.

Kiss and Tell looks set to continue this pattern, with her character possessing the gift (or curse) of knowing from that first pash whether a relationship will work out.

Isla Fisher, Andy Serkis and Tom Wilkinson have joined Simon Pegg in “Burke and Hare,” a horror comedy that marks John Landis’ return to feature directing after more than 10 years.

Written by Piers Ashworth and Nick Moorcroft, “Hare” is based on the true story a pair of the U.K.’s earliest serial killers, William Burke and William Hare, gravediggers who lucratively sold the corpses of their victims to a medical college for dissection.

Serkis, fresh off a leading actor BAFTA nomination for “Sex & Drugs & Rock & Roll,” will play Hare opposite Pegg’s Burke. (David Tennant was tipped for the role but bowed out when he joined the NBC pilot “Rex Is Not My Lawyer.”)

Fisher will play Pegg’s girlfriend, an actress looking for a patron who might or might not be an accomplice to the murders.

Wilkinson will play Dr. Robert Knox, an anatomy lecturer looking for fresh corpses.

The movie begins shooting Jan. 31 in Edinburgh and London, bringing Landis back to the scene of his 1981 hit “An American Werewolf in London.”

Barnaby Thompson is producing; Ealing Studios’ James Spring is executive producing.

Fisher, repped by CAA and Mosaic, most recently appeared in “Confessions of a Shopaholic.”

Serkis, repped by Lou Coulson Associates and Principal Entertainment, is best known for his work as Gollum in the “Lord of the Rings” movies and in “King Kong.” He is portrays Captain Haddock in Steven Spielberg’s “The Adventures of Tintin: The Secret of the Unicorn.”

Wilkinson next appears in Roman Polanski’s “The Ghost Writer” and recently wrapped shooting Michel Gondry’s “The Green Hornet” for Sony

Isla Fisher is eyeing “Desperados,” a feature comedy described as a female-oriented “Hangover.”

The story is set in motion when a woman sends an indignant e-mail to her new beau, who’s gone silent after they have sex. When she discovers he’s comatose in a Mexican hospital, she races south of the border with her friends in tow to intercept the e-mail before he recovers.

The project is being developed at Universal by Mark Gordon (“2012″) and Jason Blum, one of the producers behind the surprise horror hit “Paranormal Activity.” It was written by Ellen Rapoport.

Fisher, the Australia-raised fiancee of “Borat” star Sacha Baron Cohen, last starred in “Confessions of a Shopaholic.” She made her breakthrough as a twisted bridesmaid in 2005’s “Wedding Crashers.”

Source: Reuters